Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29118704 | 0.85 | DHODH (0.43) | NPSR1MAPK14MAPK13RAF1MAPK12 | |
| SCHEMBL29118670 | 0.80 | RAB9A (0.43) | ADORA1ALDH1A1LMNAMAPK14KMT2A | |
| SCHEMBL25847343 | 0.80 | CYP1A2 (0.42) | ADORA2AADORA1ALDH1A1LMNACYP1A2 | |
| SCHEMBL10983261 | 0.79 | ADORA2A (0.45) | ADORA2AADORA1ALDH1A1LMNANPSR1 | |
| SCHEMBL10671008 | 0.79 | PDE10A (0.47) | ADORA2AADORA1ALDH1A1LMNAKMT2A | |
| SCHEMBL10986938 | 0.78 | KMO (0.52) | ADORA2AADORA1ALDH1A1LMNANPSR1 | |
| SCHEMBL11976488 | 0.78 | TDO2 (0.60) | ADORA2AADORA1ALDH1A1LMNANPSR1 | |
| SCHEMBL8470699 | 0.77 | ABCG2 (0.37) | ADORA2AALDH1A1LMNACYP1A2HPGD | |
| SCHEMBL29118727 | 0.77 | NPC1 (0.43) | ALDH1A1LMNANPSR1TDO2KMT2A | |
| SCHEMBL10992698 | 0.77 | PARP1 (0.49) | ADORA2AADORA1ALDH1A1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499094-A | PREVENTION OF RESPIRATORY, UROGENITAL, CARDIOVASCULAR AND IMMUNOLOGICAL DISORDERS WHEN USING FOR BENZDIAPINES | PHARMUKA LABORATOIRES (FR) | 1985-02-12 | — | — | US | disclosed |