Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7122560 | 0.80 | ALDH1A1 (0.35) | LMNAKDM4EPKMMEN1KMT2A | |
| SCHEMBL7122559 | 0.78 | ALDH1A1 (0.34) | LMNAKDM4EPKMMEN1KMT2A | |
| SCHEMBL543816 | 0.75 | CYP4F2 (0.35) | SMN1; SMN2LMNAKDM4EPKMMEN1 | |
| SCHEMBL4284951 | 0.69 | — | — | |
| SCHEMBL10590584 | 0.67 | PPARD (0.35) | LMNAKDM4EPKMMEN1KMT2A | |
| SCHEMBL27603424 | 0.67 | MEN1 (0.44) | SMN1; SMN2LMNAKDM4EPKMMEN1 | |
| SCHEMBL7829298 | 0.66 | ALDH1A1 (0.37) | LMNAKDM4EPKMMEN1KMT2A | |
| SCHEMBL16658461 | 0.66 | CYP4F2 (0.39) | SMN1; SMN2LMNAKDM4EPKMMEN1 | |
| SCHEMBL4284948 | 0.66 | — | — | |
| SCHEMBL9283162 | 0.65 | PKM (0.39) | LMNAKDM4EPKMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4536592-A | ANTISECRETORY AGENT | G. D. SEARLE & CO. (US) | 1985-08-20 | — | — | US | disclosed |