Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3626070 | 0.83 | PKM (0.36) | PKMKDM4ECYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL18759662 | 0.75 | CYP4F2 (0.40) | PKMKDM4ECYP4F2CYP4A11PIN1 | |
| SCHEMBL16048 | 0.75 | CYP4F2 (0.40) | PKMKDM4ECYP4F2CYP4A11PIN1 | |
| SCHEMBL2238297 | 0.73 | PKM (0.41) | PKMKDM4ECYP4F2CYP4A11PIN1 | |
| SCHEMBL19278938 | 0.73 | CYP4F2 (0.39) | PKMKDM4ECYP4F2CYP4A11PIN1 | |
| SCHEMBL413276 | 0.73 | CYP4F2 (0.39) | PKMKDM4ECYP4F2CYP4A11PIN1 | |
| SCHEMBL647742 | 0.73 | TSHR (0.33) | PKMKDM4ECYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL2239052 | 0.73 | CYP4F2 (0.36) | PKMKDM4ECYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL1450701 | 0.72 | CYP4F2 (0.41) | PKMKDM4ECYP4F2CYP4A11PIN1 | |
| SCHEMBL29101187 | 0.72 | CYP4F2 (0.38) | PKMKDM4ECYP4F2CYP4A11PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140249105-A1 | NOVEL CERAMIDE ANALOGUES, PROCESSES FOR PREPARING SAME AND USES THEREOF | DIVERCHIM (FR) | 2014-09-04 | — | — | US | disclosed |
| EP-0521752-B1 | Process for the preparation of alpha fluorinated acrylates | ATOCHEM ELF SA (FR) | 1995-03-22 | — | — | EP | disclosed |
| EP-0402246-B1 | Thiazolylalkoxyacrylates, process for their preparation, their use as fungicides and intermediates in their preparation | ROUSSEL UCLAF (FR) | 1994-08-24 | — | — | EP | disclosed |
| EP-0402246-A1 | Thiazolylalkoxyacrylates, process for their preparation, their use as fungicides and intermediates in their preparation | ROUSSEL-UCLAF (FR) | 1990-12-12 | — | — | EP | disclosed |
| EP-0050534-B1 | ESTERS OF CYCLOPROPANE-CARBOXYLIC ACIDS RELATED TO PYRETHRIC ACID, THEIR PREPARATION AND USE AS INSECTICIDES | ROUSSEL-UCLAF (FR) | 1985-04-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140249105-A1 | NOVEL CERAMIDE ANALOGUES, PROCESSES FOR PREPARING SAME AND USES THEREOF | CERS2, CERT1, SGMS2 | PKM 4061/4885KDM4E 3384/4885CYP4F2 1555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.