Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.64 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4977496 | 0.98 | ZDHHC20 (0.61) | ZDHHC20ZDHHC2KDM4EALDH1A1KDM5A | |
| SCHEMBL111362 | 0.93 | ZDHHC20 (0.58) | ZDHHC20ZDHHC2KDM4EALDH1A1KDM5A | |
| SCHEMBL18331464 | 0.90 | ZDHHC20 (0.62) | ZDHHC20ZDHHC2KDM4EALDH1A1TGM2 | |
| SCHEMBL17325028 | 0.88 | ZDHHC20 (0.59) | ZDHHC20ZDHHC2KDM4EALDH1A1KDM5A | |
| SCHEMBL18331600 | 0.88 | ZDHHC20 (0.59) | ZDHHC20ZDHHC2KDM4EALDH1A1TGM2 | |
| SCHEMBL18331536 | 0.88 | ZDHHC20 (0.59) | ZDHHC20ZDHHC2KDM4EALDH1A1KDM5A | |
| SCHEMBL18331525 | 0.88 | ZDHHC20 (0.59) | ZDHHC20ZDHHC2KDM4EALDH1A1KDM5A | |
| SCHEMBL18331465 | 0.88 | ZDHHC20 (0.59) | ZDHHC20ZDHHC2KDM4EALDH1A1KDM5A | |
| SCHEMBL109865 | 0.86 | ZDHHC20 (0.52) | ZDHHC20ZDHHC2KDM4EALDH1A1KDM5A | |
| SCHEMBL18331462 | 0.86 | ZDHHC20 (0.56) | ZDHHC20ZDHHC2KDM4EALDH1A1KDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424491-A2 | FILM FORMER IN HAIR DYES | Henkel AG & Co. KGaA (DE) | 2012-03-07 | — | — | EP | disclosed |
| WO-2010124897-A2 | FILM FORMER IN HAIR DYES | HENKEL AG & CO. KGAA (DE) | 2010-11-04 | — | — | WO | disclosed |