Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.61 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL109873 | 0.98 | ZDHHC20 (0.64) | ZDHHC20ZDHHC2ALDH1A1KDM5AKDM4C | |
| SCHEMBL111362 | 0.95 | ZDHHC20 (0.58) | ZDHHC20ZDHHC2ALDH1A1KDM5AKDM4C | |
| SCHEMBL18331600 | 0.89 | ZDHHC20 (0.59) | ZDHHC20ZDHHC2ALDH1A1KDM4ETSHR | |
| SCHEMBL18331464 | 0.88 | ZDHHC20 (0.62) | ZDHHC20ZDHHC2ALDH1A1KDM4ETSHR | |
| SCHEMBL18331462 | 0.87 | ZDHHC20 (0.56) | ZDHHC20ZDHHC2ALDH1A1KDM5AKDM4C | |
| SCHEMBL109865 | 0.87 | ZDHHC20 (0.52) | ZDHHC20ZDHHC2ALDH1A1KDM5AKDM4C | |
| SCHEMBL18331465 | 0.86 | ZDHHC20 (0.59) | ZDHHC20ZDHHC2ALDH1A1KDM5AKDM4C | |
| SCHEMBL18331525 | 0.86 | ZDHHC20 (0.59) | ZDHHC20ZDHHC2ALDH1A1KDM5AKDM4C | |
| SCHEMBL17325028 | 0.86 | ZDHHC20 (0.59) | ZDHHC20ZDHHC2ALDH1A1KDM5AKDM4C | |
| SCHEMBL18331536 | 0.86 | ZDHHC20 (0.59) | ZDHHC20ZDHHC2ALDH1A1KDM5AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11578060-B2 | JAK3 selective inhibitor | PEKING UNIVERSITY SHENZHEN GRADUATE SCHOOL (CN) | 2023-02-14 | — | — | US | disclosed |
| EP-2818505-B1 | TIRE RUBBER COMPOSITION AND PNEUMATIC TIRE | SUMITOMO RUBBER IND (JP) | 2017-02-01 | — | — | EP | disclosed |
| EP-2787033-B1 | RUBBER COMPOSITION FOR TYRE, AND PNEUMATIC TYRE | SUMITOMO RUBBER IND (JP) | 2016-09-14 | — | — | EP | disclosed |
| US-9340663-B2 | Rubber composition for tire, and pneumatic tire | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2016-05-17 | — | — | US | disclosed |
| EP-2818505-A1 | TIRE RUBBER COMPOSITION AND PNEUMATIC TIRE | Sumitomo Rubber Industries, Ltd. (JP) | 2014-12-31 | — | — | EP | disclosed |
| US-20140371372-A1 | TIRE RUBBER COMPOSITION AND PNEUMATIC TIRE | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2014-12-18 | — | — | US | disclosed |
| US-20140323660-A1 | RUBBER COMPOSITION FOR TIRE, AND PNEUMATIC TIRE | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2014-10-30 | — | — | US | disclosed |
| US-8865836-B2 | Tire rubber composition and pneumatic tire | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2014-10-21 | — | — | US | disclosed |
| EP-2787033-A1 | RUBBER COMPOSITION FOR TYRE, AND PNEUMATIC TYRE | Sumitomo Rubber Industries, Ltd. (JP) | 2014-10-08 | — | — | EP | disclosed |
| EP-2543702-B1 | Tire rubber composition and pneumatic tire | SUMITOMO RUBBER IND (JP) | 2013-09-11 | — | — | EP | disclosed |
| US-20130012660-A1 | TIRE RUBBER COMPOSITION AND PNEUMATIC TIRE | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2013-01-10 | — | — | US | disclosed |
| EP-2543702-A1 | Tire rubber composition and pneumatic tire | SUMITOMO RUBBER INDUSTRIES LIMITED (JP) | 2013-01-09 | — | — | EP | disclosed |
| US-7339005-B2 | Process for producing modified diene polymer rubber | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-03-04 | — | — | US | disclosed |
| US-20040152845-A1 | Process for producing modified diene polymer rubber | SUMITOMO CHEMICAL COMPANY, LIMITED | 2004-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11578060-B2 | JAK3 selective inhibitor | JAK3, JAK1, JAK2 | ZDHHC20 2680/4885ZDHHC2 2786/4885ALDH1A1 3055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.