SCHEMBL109865

SCHEMBL109865

C=CC(=O)NCCN(C)CC

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 1/20 0.52
ZDHHC2 Q9UIJ5 1/20 0.52
ALDH1A1 P00352 4/20 0.45
TSHR P16473 3/20 0.45
MAPK1 P28482 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
TGM2 P21980 3/20 0.35
CD274 Q9NZQ7 1/20 0.35
GAA P10253 1/20 0.35
KDM5A P29375 1/20 0.34
KDM4C Q9H3R0 1/20 0.34
KDM4E B2RXH2 2/20 0.33
DNM1 Q05193 1/20 0.33
MEN1 O00255 1/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32
FAAH O00519 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12301856 0.90 ZDHHC20 (0.52) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL111362 0.89 ZDHHC20 (0.58) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL4977496 0.87 ZDHHC20 (0.61) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL5677655 0.87 ZDHHC20 (0.55) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL109873 0.86 ZDHHC20 (0.64) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL17858061 0.85 ZDHHC20 (0.52) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL7057092 0.85 ZDHHC20 (0.56) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL6341877 0.84 ZDHHC20 (0.61) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL12301858 0.82 ZDHHC20 (0.53) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL109970 0.82 ZDHHC20 (0.53) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0472204-B1 Surface treated materials of excellent adhesion for painting layer, corrosion resistance after painting, and press formability, as well as a method of manufacturing them KOBE STEEL LTD (JP) 1996-04-24 EP claimed
US-11578060-B2 JAK3 selective inhibitor PEKING UNIVERSITY SHENZHEN GRADUATE SCHOOL (CN) 2023-02-14 US disclosed
EP-2217827-B1 SUSPENSION SYSTEM FOR AIRCRAFT AUXILIARY POWER UNIT WITH ELASTOMERIC MEMBER LORD CORP (US) 2020-06-03 EP disclosed
EP-2818505-B1 TIRE RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2017-02-01 EP disclosed
EP-2787033-B1 RUBBER COMPOSITION FOR TYRE, AND PNEUMATIC TYRE SUMITOMO RUBBER IND (JP) 2016-09-14 EP disclosed
US-9340663-B2 Rubber composition for tire, and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2016-05-17 US disclosed
CN-102863666-B Rubber composition for tire and pneumatic tyre SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2016-03-02 CN disclosed
CN-103958591-B Rubber composition for tire and pneumatic tyre SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2016-02-03 CN disclosed
EP-2818505-A1 TIRE RUBBER COMPOSITION AND PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2014-12-31 EP disclosed
US-20140371372-A1 TIRE RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2014-12-18 US disclosed
EP-0472204-B1 Surface treated materials of excellent adhesion for painting layer, corrosion resistance after painting, and press formability, as well as a method of manufacturing them KOBE STEEL LTD (JP) 1996-04-24 EP disclosed
EP-0334042-B1 Modified diene polymer rubbers SUMITOMO CHEMICAL CO (JP) 1993-11-18 EP disclosed
EP-0341496-B1 Modified diene polymer rubbers SUMITOMO CHEMICAL CO (JP) 1993-10-20 EP disclosed
US-5219938-A Reacting a living polymer of a conjugated diene with a tin or silicon compound and with a nitro compound, a phosphoryl chloride, aminosilane, an acrylamide or an aminovinylsilane; auto tires; impact strength; cold resistance; storage SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-06-15 US disclosed
US-5189109-A Acrylamide modified; impact strength; automobile tire SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-02-23 US disclosed
US-5169726-A A zinc or iron series plating layer; a (meth)acrylic polymer having repeating units of a (meth)acrylic acid derivative containing an epoxy group KABUSHIKI KAISHA KOBE SEIKO SHO (JP) 1992-12-08 US disclosed
US-5128416-A Automobile tire treads SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-07-07 US disclosed
EP-0472204-A2 Surface treated materials of excellent adhesion for painting layer, corrosion resistance after painting, and press formability, as well as a method of manufacturing them KABUSHIKI KAISHA KOBE SEIKO SHO (JP) 1992-02-26 EP disclosed
EP-0341496-A2 Modified diene polymer rubbers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-11-15 EP disclosed
EP-0334042-A2 Modified diene polymer rubbers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-09-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11578060-B2 JAK3 selective inhibitor JAK3, JAK1, JAK2 ZDHHC20 2680/4885ZDHHC2 2786/4885ALDH1A1 3055/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.