Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 2/20 | 0.53 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.51 |
| ▸ | MT-CO2 | P00403 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | FABP4 | P15090 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10987377 | 0.85 | MT-CO2 (0.49) | CXCR2SIRT2MT-CO2MAPTALOX15 | |
| SCHEMBL10987263 | 0.83 | MAPT (0.51) | SIRT2MT-CO2MAPTALOX15FABP4 | |
| SCHEMBL10983702 | 0.83 | MEN1 (0.56) | SIRT2MT-CO2MAPTALOX15MEN1 | |
| SCHEMBL10838240 | 0.83 | MAPK9 (0.53) | CXCR2SIRT2MAPTALOX15MAPK9 | |
| SCHEMBL10992516 | 0.82 | MAPT (0.64) | SIRT2MT-CO2MAPTMEN1KMT2A | |
| SCHEMBL10936401 | 0.81 | MEN1 (0.58) | SIRT2MT-CO2MAPTALOX15FABP4 | |
| SCHEMBL10835189 | 0.80 | FABP4 (0.73) | SIRT2MT-CO2MAPTALOX15FABP4 | |
| SCHEMBL10991979 | 0.79 | POLB (0.63) | CXCR2SIRT2MT-CO2MAPTALOX15 | |
| SCHEMBL10992166 | 0.79 | TP53 (0.53) | SIRT2MT-CO2MAPTALOX15FABP4 | |
| SCHEMBL10984674 | 0.78 | SIRT2 (0.69) | SIRT2MT-CO2FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4549016-A | LIPOXYGENASE INHIBITORS, ANTIALLERGENS, ANTIASTHMA AGENTS | STERLING DRUG INC. (US) | 1985-10-22 | — | — | US | disclosed |
| US-4510139-A | ANTYIALLERGENS; ASTHMA | STERLING DRUG INC. (US) | 1985-04-09 | — | — | US | disclosed |