Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | MT-CO2 | P00403 | 2/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10992166 | 0.92 | TP53 (0.53) | MAPTMT-CO2ADRA1DADRA1AADRA1B | |
| SCHEMBL14349252 | 0.89 | MAPT (0.57) | MAPTMT-CO2ADRA1DADRA1AADRA1B | |
| SCHEMBL10987377 | 0.87 | MT-CO2 (0.49) | MAPTMT-CO2ADRA1DADRA1AADRA1B | |
| SCHEMBL10988251 | 0.85 | MEN1 (0.53) | MAPTMT-CO2ALOX15PKMNPC1 | |
| SCHEMBL10839355 | 0.84 | ADRA1A (0.52) | MAPTADRA1DADRA1AADRA1BABCC1 | |
| SCHEMBL10987315 | 0.83 | CXCR2 (0.53) | MAPTMT-CO2SMN1; SMN2ALOX15SIRT2 | |
| SCHEMBL10989940 | 0.81 | GRM5 (0.46) | MAPTMT-CO2NPC1RAB9AMEN1 | |
| SCHEMBL10992516 | 0.78 | MAPT (0.64) | MAPTMT-CO2ABCC1SIRT2NPC1 | |
| SCHEMBL27752030 | 0.78 | ADRA1A (0.57) | MAPTADRA1DADRA1AADRA1BABCC1 | |
| SCHEMBL10936401 | 0.78 | MEN1 (0.58) | MAPTMT-CO2ALOX15SIRT2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4549016-A | LIPOXYGENASE INHIBITORS, ANTIALLERGENS, ANTIASTHMA AGENTS | STERLING DRUG INC. (US) | 1985-10-22 | — | — | US | disclosed |
| US-4510139-A | ANTYIALLERGENS; ASTHMA | STERLING DRUG INC. (US) | 1985-04-09 | — | — | US | disclosed |