Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10987790 | 0.87 | GAA (0.54) | GAATDP1KMT2AALDH1A1KDM4E | |
| SCHEMBL10984567 | 0.80 | HTR1A (0.50) | KMT2ALMNAHTR1ADRD2POLB | |
| SCHEMBL3426125 | 0.78 | GAA (0.52) | GAATDP1KMT2AALDH1A1KDM4E | |
| SCHEMBL10987363 | 0.76 | LMNA (0.50) | GAAKMT2ALMNAL3MBTL1 | |
| SCHEMBL10987750 | 0.74 | GAA (0.42) | GAATDP1ALDH1A1L3MBTL1 | |
| SCHEMBL10982815 | 0.74 | APP (0.42) | GAATDP1 | |
| SCHEMBL11443757 | 0.71 | GAA (0.48) | GAATDP1KMT2AALDH1A1KDM4E | |
| SCHEMBL10834487 | 0.71 | MAPT (0.36) | GAATDP1KMT2AALDH1A1KDM4E | |
| SCHEMBL134467 | 0.71 | HSP90AB1 (0.35) | TDP1KMT2AALDH1A1LMNAHTR1A | |
| SCHEMBL10989493 | 0.71 | CDK1 (0.32) | ALDH1A1HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4528026-A | 2-(Or4-)amino-5-alkylthio-pyrimidine herbicides | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1985-07-09 | — | — | US | disclosed |