Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 3/20 | 0.48 |
| ▸ | RIN1 | Q13671 | 3/20 | 0.48 |
| ▸ | XDH | P47989 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10981661 | 0.81 | ABL1 (0.51) | ABL1RIN1XDHCYP3A4BLM | |
| SCHEMBL9543645 | 0.75 | ABL1 (0.56) | ABL1RIN1XDHCYP3A4BLM | |
| SCHEMBL1367663 | 0.73 | ABL1 (0.57) | ABL1RIN1XDHCYP3A4BLM | |
| SCHEMBL9543202 | 0.71 | BACE1 (0.57) | ABL1RIN1XDHCYP3A4BLM | |
| SCHEMBL9542420 | 0.71 | ABL1 (0.55) | ABL1RIN1XDHCYP3A4BLM | |
| SCHEMBL10988809 | 0.70 | MAPT (0.51) | KMT2A | |
| SCHEMBL2087960 | 0.69 | FBP1 (0.46) | CYP3A4KMT2AKDM4E | |
| SCHEMBL9543525 | 0.69 | ABL1 (0.59) | ABL1RIN1XDHCYP3A4BLM | |
| SCHEMBL13327841 | 0.68 | PKM (0.42) | KMT2AKDM4E | |
| SCHEMBL26980532 | 0.68 | CYP3A4 (0.55) | ABL1RIN1XDHCYP3A4BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4549019-A | Pyrimidinecarbamate derivatives as intermediates | HOFFMANN-LA ROCHE INC. (US) | 1985-10-22 | — | — | US | disclosed |