Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | RAB9A | P51151 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.60 |
| ▸ | SNCA | P37840 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | FBP1 | P09467 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434245 | 1.00 | MAPT (0.64) | MAPTRAB9AALDH1A1GLO1SNCA | |
| SCHEMBL9433640 | 0.86 | RAB9A (0.62) | MAPTRAB9AALDH1A1SNCANPC1 | |
| SCHEMBL9433771 | 0.86 | RAB9A (0.62) | MAPTRAB9AALDH1A1SNCANPC1 | |
| SCHEMBL9433701 | 0.86 | GLO1 (0.64) | MAPTRAB9AALDH1A1GLO1SNCA | |
| SCHEMBL9433707 | 0.86 | GLO1 (0.64) | MAPTRAB9AALDH1A1GLO1SNCA | |
| SCHEMBL9433972 | 0.86 | SMN1; SMN2 (0.61) | MAPTRAB9AALDH1A1GLO1POLB | |
| SCHEMBL9433982 | 0.86 | SMN1; SMN2 (0.61) | MAPTRAB9AALDH1A1GLO1POLB | |
| SCHEMBL9433715 | 0.84 | GLO1 (0.59) | MAPTRAB9AALDH1A1GLO1SNCA | |
| SCHEMBL9433735 | 0.84 | GLO1 (0.59) | MAPTRAB9AALDH1A1GLO1SNCA | |
| SCHEMBL9434279 | 0.83 | GLO1 (0.64) | MAPTRAB9AALDH1A1GLO1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3002161-A | — | — | None | — | — | JP | disclosed |
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| JP-H032161-A | 1,4-DIHYDROPYRIDINE DERIVATIVE | FUJIREBIO INC | 1991-01-08 | — | — | JP | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |