Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10988801 | 1.00 | GRM5 (0.54) | GRM5KMT2AMEN1POLBTSHR | |
| SCHEMBL10993528 | 0.87 | GRM5 (0.58) | GRM5KMT2AMEN1POLBTSHR | |
| SCHEMBL10998692 | 0.83 | GRM5 (0.59) | GRM5LMNA | |
| SCHEMBL10990477 | 0.83 | GRM5 (0.54) | GRM5KMT2AMEN1POLBTSHR | |
| SCHEMBL10998992 | 0.80 | GRM5 (0.51) | GRM5KMT2AMEN1POLBTSHR | |
| SCHEMBL10997257 | 0.80 | GRM5 (0.55) | GRM5KMT2AMEN1POLBTSHR | |
| SCHEMBL10997260 | 0.80 | GRM5 (0.55) | GRM5KMT2AMEN1POLBTSHR | |
| SCHEMBL11233767 | 0.78 | GRM5 (0.73) | GRM5POLBRAB9AALDH1A1MAPT | |
| SCHEMBL11233774 | 0.78 | GRM5 (0.73) | GRM5POLBRAB9AALDH1A1MAPT | |
| SCHEMBL10996662 | 0.78 | GRM5 (0.59) | GRM5KMT2AMEN1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4542144-A | EPILEPSY | MCNEILAB INC. (US) | 1985-09-17 | — | — | US | claimed |