Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.54 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10993528 | 0.93 | GRM5 (0.58) | GRM5TP53NPC1RAB9APOLB | |
| SCHEMBL10998692 | 0.89 | GRM5 (0.59) | GRM5TP53HPGDP2RX7 | |
| SCHEMBL10993124 | 0.88 | GRM5 (0.62) | GRM5NPC1RAB9APOLBATM | |
| SCHEMBL10993126 | 0.88 | GRM5 (0.62) | GRM5NPC1RAB9APOLBATM | |
| SCHEMBL10998992 | 0.86 | GRM5 (0.51) | GRM5TP53NPC1RAB9APOLB | |
| SCHEMBL11000472 | 0.86 | GRM5 (0.39) | GRM5RIPK1TP53POLBATM | |
| SCHEMBL10988801 | 0.83 | GRM5 (0.54) | GRM5RAB9APOLBALDH1A1GAA | |
| SCHEMBL10988804 | 0.83 | GRM5 (0.54) | GRM5RAB9APOLBALDH1A1GAA | |
| SCHEMBL10992172 | 0.83 | GRM5 (0.63) | GRM5NPC1RAB9APOLBGAA | |
| SCHEMBL10992189 | 0.83 | GRM5 (0.63) | GRM5NPC1RAB9APOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4542144-A | EPILEPSY | MCNEILAB INC. (US) | 1985-09-17 | — | — | US | disclosed |