Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | RBP4 | P02753 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10993528 | 0.90 | GRM5 (0.58) | GRM5TSHRPOLBTP53MEN1 | |
| SCHEMBL10994198 | 0.89 | GRM5 (0.59) | GRM5TSHRPABPC1POLBMEN1 | |
| SCHEMBL10994194 | 0.89 | GRM5 (0.59) | GRM5TSHRPABPC1POLBMEN1 | |
| SCHEMBL10994676 | 0.87 | ATM (0.38) | GRM5TSHRSLC6A9POLBTP53 | |
| SCHEMBL10990477 | 0.86 | GRM5 (0.54) | GRM5TSHRPOLBTP53MEN1 | |
| SCHEMBL10998692 | 0.86 | GRM5 (0.59) | GRM5TP53LMNA | |
| SCHEMBL10991240 | 0.85 | GRM5 (0.55) | GRM5TSHRPABPC1POLBMEN1 | |
| SCHEMBL10991224 | 0.84 | GRM5 (0.59) | GRM5TSHRPABPC1POLBMEN1 | |
| SCHEMBL10988804 | 0.80 | GRM5 (0.54) | GRM5TSHRPOLBMEN1KMT2A | |
| SCHEMBL10988801 | 0.80 | GRM5 (0.54) | GRM5TSHRPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4542144-A | EPILEPSY | MCNEILAB INC. (US) | 1985-09-17 | — | — | US | disclosed |