Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | CDK11A | Q9UQ88 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10989017 | 1.00 | GRM5 (0.68) | GRM5MAPTDRD1KDM4EALDH1A1 | |
| SCHEMBL10992172 | 0.93 | GRM5 (0.63) | GRM5PDK1PDK2PDK3PDK4 | |
| SCHEMBL10992189 | 0.93 | GRM5 (0.63) | GRM5PDK1PDK2PDK3PDK4 | |
| SCHEMBL10992614 | 0.92 | GRM5 (0.61) | GRM5MAPTKDM4EALDH1A1GAA | |
| SCHEMBL10991224 | 0.90 | GRM5 (0.59) | GRM5MAPTKDM4EALDH1A1GAA | |
| SCHEMBL10998692 | 0.90 | GRM5 (0.59) | GRM5PDK1PDK2PDK3PDK4 | |
| SCHEMBL10993124 | 0.85 | GRM5 (0.62) | GRM5MAPTKDM4EALDH1A1GAA | |
| SCHEMBL10993126 | 0.85 | GRM5 (0.62) | GRM5MAPTKDM4EALDH1A1GAA | |
| SCHEMBL10996908 | 0.84 | GRM5 (0.61) | GRM5MAPTKDM4EALDH1A1NLRP3 | |
| SCHEMBL10996903 | 0.84 | GRM5 (0.61) | GRM5MAPTKDM4EALDH1A1NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4542144-A | EPILEPSY | MCNEILAB INC. (US) | 1985-09-17 | — | — | US | claimed |
| US-4542144-A | EPILEPSY | MCNEILAB INC. (US) | 1985-09-17 | — | — | US | disclosed |