Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10996908 | 1.00 | GRM5 (0.61) | GRM5MAPTRAB9ATP53GAA | |
| SCHEMBL10992614 | 0.92 | GRM5 (0.61) | GRM5MAPTRAB9ATP53GAA | |
| SCHEMBL10993126 | 0.85 | GRM5 (0.62) | GRM5MAPTRAB9AGAAKDM4E | |
| SCHEMBL10993124 | 0.85 | GRM5 (0.62) | GRM5MAPTRAB9AGAAKDM4E | |
| SCHEMBL10989729 | 0.84 | GRM5 (0.61) | GRM5MAPTRAB9AKDM4EKMT2A | |
| SCHEMBL10989727 | 0.84 | GRM5 (0.61) | GRM5MAPTRAB9AKDM4EKMT2A | |
| SCHEMBL10989017 | 0.84 | GRM5 (0.68) | GRM5MAPTRAB9AGAAKDM4E | |
| SCHEMBL10989034 | 0.84 | GRM5 (0.68) | GRM5MAPTRAB9AGAAKDM4E | |
| SCHEMBL10993528 | 0.84 | GRM5 (0.58) | GRM5MAPTRAB9ATP53KDM4E | |
| SCHEMBL10995246 | 0.83 | GRM5 (0.60) | GRM5RAB9AKDM4EKMT2ANLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4542144-A | EPILEPSY | MCNEILAB INC. (US) | 1985-09-17 | — | — | US | claimed |