Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11828499 | 0.87 | TDP1 (0.39) | PGK1MAPTTDP1TSHRKDM4E | |
| Hydrochloric Acid SCHEMBL11497807 | 0.74 | TDP1 (0.41) | PGK1MAPTTDP1TSHRKDM4E | |
| SCHEMBL11826371 | 0.73 | MAPT (0.43) | MAPTKMT2AHTT | |
| SCHEMBL30381851 | 0.71 | HSP90AB1 (0.35) | TDP1KMT2AALDH1A1 | |
| SCHEMBL134467 | 0.71 | HSP90AB1 (0.35) | TDP1KMT2AALDH1A1 | |
| SCHEMBL10989493 | 0.71 | CDK1 (0.32) | TSHRALOX15ALDH1A1 | |
| SCHEMBL10984617 | 0.71 | ADORA3 (0.36) | PGK1MAPTTDP1KMT2AGAA | |
| Bromide SCHEMBL11827311 | 0.69 | PLAU (0.37) | TDP1KDM4EKMT2AGAAHTT | |
| SCHEMBL10987363 | 0.69 | LMNA (0.50) | MAPTKMT2AGAA | |
| SCHEMBL11834919 | 0.68 | SLC29A1 (0.33) | TDP1TSHRKDM4EGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4528026-A | 2-(Or4-)amino-5-alkylthio-pyrimidine herbicides | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1985-07-09 | — | — | US | claimed |
| EP-0000681-B1 | AMINO-2 (OR -4) ALKYLTHIO-5 PYRIMIDINES, PROCESSES FOR THEIR PREPARATION, THEIR USE AS HERBICIDES AND COMPOSITION CONTAINING THEM | P C U K PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1981-08-26 | — | — | EP | claimed |
| US-4528026-A | 2-(Or4-)amino-5-alkylthio-pyrimidine herbicides | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1985-07-09 | — | — | US | disclosed |