Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 7/20 | 0.40 |
| ▸ | CA2 | P00918 | 7/20 | 0.40 |
| ▸ | CA12 | O43570 | 6/20 | 0.40 |
| ▸ | CA7 | P43166 | 6/20 | 0.40 |
| ▸ | CA9 | Q16790 | 6/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAD1 | O60671 | 1/20 | 0.34 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10995734 | 0.87 | L3MBTL1 (0.42) | CA1CA2ALDH1A1MAPTHPGD | |
| SCHEMBL10917876 | 0.83 | ALDH1A1 (0.45) | CA1CA2CA12CA7CA9 | |
| SCHEMBL10923552 | 0.73 | CA12 (0.46) | CA1CA2CA12CA7CA9 | |
| SCHEMBL9652526 | 0.71 | TRPA1 (0.49) | CA1CA2CA12CA7CA9 | |
| SCHEMBL8929753 | 0.70 | MAPK1 (0.50) | CA1CA2CA12CA7CA9 | |
| SCHEMBL1928503 | 0.69 | NPC1 (0.54) | CA1CA2CA12CA7CA9 | |
| SCHEMBL30784110 | 0.69 | NPC1 (0.54) | CA1CA2CA12CA7CA9 | |
| SCHEMBL9858564 | 0.68 | MAPK1 (0.50) | CA1CA2CA12CA7CA9 | |
| SCHEMBL6154714 | 0.68 | P2RY6 (0.45) | CA1CA2KDM4EALDH1A1MAPT | |
| SCHEMBL28786081 | 0.67 | CA12 (0.50) | CA1CA2CA12CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4561880-A | 1H[1,2,4]-Triazolo[1,2-a]pyridazine-1,3-diones useful as herbicides | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1985-12-31 | — | — | US | disclosed |
| EP-0104484-A1 | A heterocyclic compound and its use as herbicide | Nippon Kayaku Kabushiki Kaisha (JP) | 1984-04-04 | — | — | EP | disclosed |