Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | CCR6 | P51684 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | DRD1 | P21728 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10992739 | 0.82 | HSD17B10 (0.76) | HSD17B10MEN1KMT2AMAPTTP53 | |
| SCHEMBL10991344 | 0.78 | HSD17B10 (0.45) | HSD17B10MEN1KMT2AMAPTTP53 | |
| SCHEMBL10836352 | 0.78 | HSD17B10 (0.78) | HSD17B10MEN1KMT2AMAPTTP53 | |
| SCHEMBL4152460 | 0.75 | HSD17B10 (1.00) | HSD17B10MEN1KMT2AMAPTTP53 | |
| Vincantril SCHEMBL2734148 | 0.75 | HSD17B10 (0.39) | HSD17B10MEN1KMT2AMAPTTP53 | |
| SCHEMBL13702963 | 0.74 | KMT2A (0.98) | HSD17B10MEN1KMT2AMAPTTP53 | |
| Pirlindole SCHEMBL373564 | 0.73 | HSD17B10 (1.00) | HSD17B10MEN1KMT2AMAPTTP53 | |
| Pirlindole SCHEMBL18877133 | 0.73 | HSD17B10 (1.00) | HSD17B10MEN1KMT2AMAPTTP53 | |
| Pirlindole SCHEMBL29500947 | 0.73 | HSD17B10 (1.00) | HSD17B10MEN1KMT2AMAPTTP53 | |
| Pirlindole SCHEMBL18878061 | 0.73 | HSD17B10 (1.00) | HSD17B10MEN1KMT2AMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4503058-A | ANTIANOXIC | SYNTHELABO (FR) | 1985-03-05 | — | — | US | claimed |
| US-4503058-A | ANTIANOXIC | SYNTHELABO (FR) | 1985-03-05 | — | — | US | disclosed |