Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Vincantril SCHEMBL2734148 | 0.93 | HSD17B10 (0.39) | HSD17B10MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL11470919 | 0.83 | HSD17B10 (0.57) | HSD17B10MEN1KMT2ACYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL11469730 | 0.81 | HSD17B10 (0.60) | HSD17B10MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL10989925 | 0.78 | HSD17B10 (0.60) | HSD17B10MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL11445321 | 0.78 | PER2 (0.41) | HSD17B10MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL10836067 | 0.75 | HSD17B10 (0.50) | HSD17B10MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL11067724 | 0.70 | HTR1A (0.53) | HSD17B10KMT2AKDM4EGAAHTR1A | |
| SCHEMBL10491456 | 0.68 | LMNA (0.35) | HSD17B10MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL9401798 | 0.67 | LMNA (0.40) | HSD17B10CYP1A2CYP2D6KDM4ECYP3A4 | |
| SCHEMBL4972027 | 0.66 | MAPT (0.46) | HSD17B10MEN1KMT2ACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4425351-A | ANTIANOXIC | SYNTHELABO (FR) | 1984-01-10 | — | — | US | claimed |
| US-4503058-A | ANTIANOXIC | SYNTHELABO (FR) | 1985-03-05 | — | — | US | disclosed |
| US-4425351-A | ANTIANOXIC | SYNTHELABO (FR) | 1984-01-10 | — | — | US | disclosed |