Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 12/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.37 |
| ▸ | MAPT | P10636 | 8/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | GAA | P10253 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 10/20 | 0.34 |
| ▸ | POLB | P06746 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10996172 | 0.81 | TSHR (0.43) | TSHRRAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL10987783 | 0.72 | MEN1 (0.41) | RAB9ASMN1; SMN2MAPTALDH1A1GAA | |
| SCHEMBL10987773 | 0.72 | MEN1 (0.41) | RAB9ASMN1; SMN2MAPTALDH1A1GAA | |
| SCHEMBL10991118 | 0.70 | MAPT (0.33) | TSHRRAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL10990642 | 0.66 | MAPT (0.46) | RAB9ASMN1; SMN2MAPTALDH1A1GAA | |
| SCHEMBL10988567 | 0.66 | DYRK1A (0.48) | TSHRRAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL10993495 | 0.64 | GAA (0.32) | MAPTGAAKMT2AMEN1LMNA | |
| SCHEMBL11034895 | 0.62 | MAPT (0.50) | RAB9ASMN1; SMN2MAPTALDH1A1GAA | |
| SCHEMBL4318522 | 0.62 | GAA (0.43) | TSHRRAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL211172 | 0.62 | TSHR (0.53) | TSHRRAB9ASMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4491587-A | ANTIALLERGENS, ANTIHISTAMINES, MUSCLE RELAXANTS/ INSULATING POWDER BLANKET ABOVD THE MELT WITH HEAT GENERATED IN THE MELT BY ELECTRIC CURRENT; LOWER TEMPERATURE | MEAD JOHNSON & COMPANY (US) | 1985-01-01 | — | — | US | disclosed |
| US-4223031-A | ANTIALLERGENS, ANTIHISTAMINES, BRONCHODILATOR AGENTS, HYPERSENSITIVITY | MEAD JOHNSON & COMPANY (US) | 1980-09-16 | — | — | US | disclosed |