Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 8/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.32 |
| ▸ | NPC1 | O15118 | 5/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | STAT6 | P42226 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 4/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10996793 | 1.00 | MAPT (0.33) | MAPTHSD17B10FDPSRAB9ASMN1; SMN2 | |
| SCHEMBL10994816 | 0.79 | MAPT (0.42) | MAPTHSD17B10FDPSRAB9ASMN1; SMN2 | |
| SCHEMBL10987783 | 0.72 | MEN1 (0.41) | MAPTHSD17B10RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL10990825 | 0.70 | TSHR (0.37) | MAPTHSD17B10RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9038730 | 0.69 | MAPT (0.43) | MAPTFDPSRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9038722 | 0.69 | MAPT (0.43) | MAPTFDPSRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL4318522 | 0.67 | GAA (0.43) | MAPTHSD17B10RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL4318524 | 0.67 | GAA (0.43) | MAPTHSD17B10RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9599085 | 0.65 | GAA (0.33) | MAPTRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL15660784 | 0.62 | HSD17B10 (0.51) | MAPTHSD17B10SMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4491587-A | ANTIALLERGENS, ANTIHISTAMINES, MUSCLE RELAXANTS/ INSULATING POWDER BLANKET ABOVD THE MELT WITH HEAT GENERATED IN THE MELT BY ELECTRIC CURRENT; LOWER TEMPERATURE | MEAD JOHNSON & COMPANY (US) | 1985-01-01 | — | — | US | claimed |
| US-4491587-A | ANTIALLERGENS, ANTIHISTAMINES, MUSCLE RELAXANTS/ INSULATING POWDER BLANKET ABOVD THE MELT WITH HEAT GENERATED IN THE MELT BY ELECTRIC CURRENT; LOWER TEMPERATURE | MEAD JOHNSON & COMPANY (US) | 1985-01-01 | — | — | US | disclosed |
| US-4223031-A | ANTIALLERGENS, ANTIHISTAMINES, BRONCHODILATOR AGENTS, HYPERSENSITIVITY | MEAD JOHNSON & COMPANY (US) | 1980-09-16 | — | — | US | disclosed |