Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHAT | P28329 | 4/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL716198 | 0.91 | CHAT (0.48) | CHATMAOBNFE2L2ALDH1A1LMNA | |
| SCHEMBL336379 | 0.91 | CHAT (0.48) | CHATMAOBNFE2L2ALDH1A1LMNA | |
| SCHEMBL29260334 | 0.89 | CHAT (0.43) | CHATMAOBNFE2L2ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL4035927 | 0.89 | CHAT (0.46) | CHATMAOBNFE2L2ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL5873690 | 0.89 | CHAT (0.46) | CHATMAOBNFE2L2ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL5873693 | 0.89 | CHAT (0.46) | CHATMAOBNFE2L2ALDH1A1LMNA | |
| Formaldehyde SCHEMBL8647913 | 0.85 | CHAT (0.43) | CHATMAOBNFE2L2ALDH1A1LMNA | |
| SCHEMBL6406091 | 0.85 | CHAT (0.43) | CHATMAOBNFE2L2ALDH1A1LMNA | |
| SCHEMBL6406093 | 0.85 | CHAT (0.43) | CHATMAOBNFE2L2ALDH1A1LMNA | |
| Formaldehyde SCHEMBL8647908 | 0.85 | CHAT (0.43) | CHATMAOBNFE2L2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8772048-B2 | Fluorogenic compounds converted to fluorophores by photochemical or chemical means and their use in biological systems | KENT STATE UNIVERSITY (US) | 2014-07-08 | — | — | US | disclosed |
| US-20120190098-A1 | FLUOROGENIC COMPOUNDS CONVERTED TO FLUOROPHORES BY PHOTOCHEMICAL OR CHEMICAL MEANS AND THEIR USE IN BIOLOGICAL SYSTEMS | LELAND STANFORD JUNIOR UNIVERSITY (US) | 2012-07-26 | — | — | US | disclosed |
| US-8153446-B2 | Fluorogenic compounds converted to fluorophores by photochemical or chemical means and their use in biological systems | KENT STATE UNIVERSITY (US) | 2012-04-10 | — | — | US | disclosed |
| US-20100029952-A1 | Fluorogenic compounds converted to fluorophores by photochemical or chemical means and their use in biological systems | KENT STATE UNIVERSITY (US) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190098-A1 | FLUOROGENIC COMPOUNDS CONVERTED TO FLUOROPHORES BY PHOTOCHEMICAL OR CHEMICAL MEANS AND THEIR USE IN BIOLOGICAL SYSTEMS | MPI, ACR, PFAS | CHAT 1592/4885MAOB 262/4885NFE2L2 4233/4885 |
| US-20100029952-A1 | Fluorogenic compounds converted to fluorophores by photochemical or chemical means and their use in biological systems | MPI, ACR, PFAS | CHAT 1592/4885MAOB 262/4885NFE2L2 4233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.