Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 2/20 | 0.58 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TNKS | O95271 | 1/20 | 0.47 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.47 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.47 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27491000 | 0.85 | HSD17B1 (0.56) | HSD17B1HSD17B2ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL14159536 | 0.83 | HSD17B1 (0.64) | HSD17B1HSD17B2ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL10991848 | 0.83 | MMP13 (0.58) | HSD17B1HSD17B2ALDH1A1TDP1HTT | |
| SCHEMBL15013520 | 0.82 | HSD17B1 (0.62) | HSD17B1HSD17B2ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL13228859 | 0.82 | MAPT (0.66) | HSD17B1HSD17B2ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL10993913 | 0.82 | MMP13 (0.56) | HSD17B1HSD17B2ALDH1A1TDP1HTT | |
| SCHEMBL10990117 | 0.81 | HSD17B1 (0.58) | HSD17B1HSD17B2ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL10996146 | 0.80 | SRD5A2 (0.59) | ALDH1A1PARP10LTA4HPOLBAKR1C3 | |
| SCHEMBL27480274 | 0.79 | HSD17B1 (0.59) | HSD17B1HSD17B2ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL14159539 | 0.79 | ALDH1A1 (0.80) | HSD17B1HSD17B2ALDH1A1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4536517-A | ANTIDIABETIC, ANTILIPEMIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1985-08-20 | — | — | US | disclosed |