Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL279655 | 0.91 | ALDH1A1 (0.53) | ALDH1A1ALOX15KDM4ESMN1; SMN2LMNA | |
| SCHEMBL11373632 | 0.88 | ALDH1A1 (0.50) | ALDH1A1ALOX15KDM4ESMN1; SMN2LMNA | |
| SCHEMBL9008317 | 0.88 | ALDH1A1 (0.50) | ALDH1A1ALOX15KDM4ESMN1; SMN2LMNA | |
| SCHEMBL7596837 | 0.88 | ALDH1A1 (0.50) | ALDH1A1ALOX15KDM4ESMN1; SMN2LMNA | |
| SCHEMBL1548711 | 0.85 | NPC1 (0.43) | ALDH1A1ALOX15KDM4ESMN1; SMN2LMNA | |
| SCHEMBL4975385 | 0.83 | CES2 (0.50) | ALDH1A1ALOX15KDM4ESMN1; SMN2LMNA | |
| SCHEMBL9520491 | 0.83 | ALDH1A1 (0.50) | ALDH1A1ALOX15KDM4ESMN1; SMN2LMNA | |
| SCHEMBL286653 | 0.81 | ALDH1A1 (0.74) | ALDH1A1ALOX15KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL1099113 | 0.81 | ALDH1A1 (0.74) | ALDH1A1ALOX15KDM4ESMN1; SMN2KMT2A | |
| Benzene SCHEMBL11756425 | 0.81 | ALDH1A1 (0.74) | ALDH1A1ALOX15KDM4ESMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153682-B2 | Sulfonamides as TRPM8 modulators | JANSSEN PHARMACEUTICA, NV (BE) | 2012-04-10 | — | — | US | disclosed |