Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.50 |
| ▸ | CES1 | P23141 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL279655 | 0.91 | ALDH1A1 (0.53) | KDM4EPOLBMAPTMEN1NSD2 | |
| SCHEMBL27888980 | 0.89 | CES2 (0.61) | CES2CES1MAPTSMN1; SMN2LMNA | |
| SCHEMBL9008317 | 0.88 | ALDH1A1 (0.50) | KDM4EPOLBMAPTMEN1NSD2 | |
| SCHEMBL11373632 | 0.88 | ALDH1A1 (0.50) | KDM4EPOLBMAPTMEN1NSD2 | |
| SCHEMBL7596837 | 0.88 | ALDH1A1 (0.50) | KDM4EPOLBMAPTMEN1NSD2 | |
| SCHEMBL29875901 | 0.87 | POLB (0.57) | CES2CES1KDM4EPOLBMAPT | |
| SCHEMBL8864751 | 0.85 | ALDH1A1 (0.40) | CES2CES1KDM4EPOLBMAPT | |
| SCHEMBL9520491 | 0.83 | ALDH1A1 (0.50) | KDM4EPOLBMAPTMEN1NSD2 | |
| SCHEMBL1099217 | 0.83 | ALDH1A1 (0.46) | KDM4EPOLBMAPTMEN1NSD2 | |
| SCHEMBL286653 | 0.81 | ALDH1A1 (0.74) | KDM4EPOLBMAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080160206-A1 | DENTAL COMPOSITES BASED ON X-RAY-OPAQUE MIXED OXIDES PREPARED BY FLAME SPRAYING | BURTSCHER PETER | 2008-07-03 | — | — | US | disclosed |
| US-7335250-B2 | Dental composites based on X-ray-opaque mixed oxides prepared by flame spraying | IVOCLAR VIVADENT AG (DE) | 2008-02-26 | — | — | US | disclosed |
| US-20050176843-A1 | Dental composites based on X-ray-opaque mixed oxides prepared by flame spraying | IVOCLAR VIVADENT AG (DE) | 2005-08-11 | — | — | US | disclosed |
| US-4634602-A | COIL COATINGS; RADIATION SENSITIVE COMPOUND, RADIATION INSENSITIVE COMPOUND AND CROSSLINKING AGENT | PPG INDUSTRIES, INC. (US) | 1987-01-06 | — | — | US | disclosed |