Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.68 |
| ▸ | NPC1 | O15118 | 7/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.53 |
| ▸ | TBK1 | Q9UHD2 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10993477 | 0.89 | RAB9A (0.56) | RAB9ANPC1KMT2AMEN1RXFP1 | |
| SCHEMBL11102495 | 0.83 | RAB9A (0.72) | RAB9ANPC1KMT2AMEN1RXFP1 | |
| SCHEMBL9214814 | 0.81 | RAB9A (1.00) | RAB9ANPC1KMT2AMEN1RXFP1 | |
| SCHEMBL11102499 | 0.81 | RAB9A (0.72) | RAB9ANPC1KMT2AMEN1RXFP1 | |
| SCHEMBL10992370 | 0.76 | RAB9A (0.69) | RAB9ANPC1KMT2AMEN1RXFP1 | |
| SCHEMBL11105310 | 0.74 | KMT2A (0.80) | RAB9ANPC1KMT2AMEN1RXFP1 | |
| SCHEMBL11110654 | 0.73 | RAB9A (0.61) | RAB9ANPC1KMT2AMEN1RXFP1 | |
| SCHEMBL11104282 | 0.73 | RAB9A (0.61) | RAB9ANPC1KMT2AMEN1RXFP1 | |
| SCHEMBL11104312 | 0.72 | RAB9A (0.57) | RAB9ANPC1KMT2AMEN1RXFP1 | |
| SCHEMBL11104770 | 0.72 | RAB9A (0.59) | RAB9ANPC1KMT2AMEN1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4539326-A | REACTION OF KETOBENZOPYRAN CARBONITRILE AND KETODICARBOXYLIC ESTER | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-09-03 | — | — | US | disclosed |