Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 1.00 |
| ▸ | NPC1 | O15118 | 7/20 | 0.78 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.72 |
| ▸ | MEN1 | O00255 | 5/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | TBK1 | Q9UHD2 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9208121 | 0.86 | RAB9A (0.81) | RAB9ANPC1RXFP1KMT2AMEN1 | |
| SCHEMBL11102499 | 0.84 | RAB9A (0.72) | RAB9ANPC1RXFP1KMT2AMEN1 | |
| SCHEMBL11102495 | 0.84 | RAB9A (0.72) | RAB9ANPC1RXFP1KMT2AMEN1 | |
| SCHEMBL17072179 | 0.84 | KMT2A (0.81) | RAB9ANPC1RXFP1KMT2AMEN1 | |
| SCHEMBL10992370 | 0.82 | RAB9A (0.69) | RAB9ANPC1RXFP1KMT2AMEN1 | |
| SCHEMBL10992374 | 0.81 | RAB9A (0.68) | RAB9ANPC1RXFP1KMT2AMEN1 | |
| SCHEMBL19182246 | 0.76 | TBK1 (0.74) | RAB9ANPC1RXFP1KDM4ETBK1 | |
| SCHEMBL9213416 | 0.76 | KMT2A (0.68) | RAB9ANPC1RXFP1KMT2AMEN1 | |
| SCHEMBL9205610 | 0.76 | RAB9A (0.66) | RAB9ANPC1RXFP1KMT2AMEN1 | |
| SCHEMBL19196789 | 0.76 | TBK1 (0.80) | RAB9ANPC1RXFP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0561845-B1 | PYRIDO-ANELLATED 4-OXO-4H-BENZOPYRANS, A METHOD OF PREPARING THEM, AND THEIR USE AS ANTIDOTES | BASF AG (DE) | 1995-03-08 | — | — | EP | claimed |
| EP-0561845-A1 | PYRIDO-ANELLATED 4-OXO-4H-BENZOPYRANS, A METHOD OF PREPARING THEM, AND THEIR USE AS ANTIDOTES. | BASF AG (DE) | 1993-09-29 | — | — | EP | claimed |
| WO-1992010500-A1 | PYRIDO-ANELLATED 4-OXO-4H-BENZOPYRANS, A METHOD OF PREPARING THEM, AND THEIR USE AS ANTIDOTES | BASF AKTIENGESELLSCHAFT (DE) | 1992-06-25 | — | — | WO | claimed |
| EP-0561845-B1 | PYRIDO-ANELLATED 4-OXO-4H-BENZOPYRANS, A METHOD OF PREPARING THEM, AND THEIR USE AS ANTIDOTES | BASF AG (DE) | 1995-03-08 | — | — | EP | disclosed |