Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.56 |
| ▸ | TBK1 | Q9UHD2 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10998062 | 0.89 | RAB9A (0.69) | RAB9AKMT2AMEN1NPC1RXFP1 | |
| SCHEMBL9214814 | 0.84 | RAB9A (1.00) | RAB9AKMT2AMEN1NPC1RXFP1 | |
| SCHEMBL10992374 | 0.81 | RAB9A (0.68) | RAB9AKMT2AMEN1NPC1RXFP1 | |
| SCHEMBL11102495 | 0.80 | RAB9A (0.72) | RAB9AKMT2AMEN1NPC1RXFP1 | |
| SCHEMBL10992998 | 0.79 | RAB9A (0.58) | RAB9AKMT2AMEN1NPC1RXFP1 | |
| SCHEMBL10992370 | 0.78 | RAB9A (0.69) | RAB9AKMT2AMEN1NPC1RXFP1 | |
| SCHEMBL10991723 | 0.77 | RAB9A (0.58) | RAB9AKMT2AMEN1NPC1RXFP1 | |
| SCHEMBL10995204 | 0.77 | RAB9A (0.56) | RAB9AKMT2AMEN1NPC1RXFP1 | |
| SCHEMBL10994956 | 0.77 | RAB9A (0.58) | RAB9AKMT2AMEN1NPC1RXFP1 | |
| SCHEMBL10989695 | 0.76 | NPC1 (0.54) | RAB9AKMT2AMEN1NPC1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0102175-A1 | 5-Oxo-5H-(1)benzopyrano(2,3-b)pyridine derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1984-03-07 | — | — | EP | disclosed |