Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CHKA | P35790 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2911507 | 0.98 | MMP3 (0.40) | ALDH1A1MMP3L3MBTL1THRBATM | |
| Hydrochloric Acid SCHEMBL10956630 | 0.96 | MMP3 (0.39) | ALDH1A1MMP3L3MBTL1THRBATM | |
| SCHEMBL10985718 | 0.92 | TSHR (0.40) | ALDH1A1MMP3L3MBTL1THRBATM | |
| SCHEMBL30179212 | 0.82 | — | — | |
| SCHEMBL28894440 | 0.81 | MMP3 (0.41) | ALDH1A1MMP3TSHRLMNAGAA | |
| SCHEMBL14335568 | 0.80 | TSHR (0.37) | ALDH1A1L3MBTL1THRBATMTSHR | |
| SCHEMBL11368635 | 0.79 | MMP3 (0.42) | MMP3TSHRSMN1; SMN2GAAMAPK1 | |
| SCHEMBL16622735 | 0.77 | SMN1; SMN2 (0.47) | ALDH1A1L3MBTL1ATMTSHRSMN1; SMN2 | |
| SCHEMBL27632523 | 0.77 | MMP3 (0.41) | ALDH1A1MMP3L3MBTL1ATMHTT | |
| SCHEMBL1654758 | 0.76 | HPGD (0.44) | ALDH1A1MMP3SMN1; SMN2MAPK1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4561880-A | 1H[1,2,4]-Triazolo[1,2-a]pyridazine-1,3-diones useful as herbicides | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1985-12-31 | — | — | US | disclosed |
| EP-0104484-A1 | A heterocyclic compound and its use as herbicide | Nippon Kayaku Kabushiki Kaisha (JP) | 1984-04-04 | — | — | EP | disclosed |
| US-4249934-A | 1,2-Alkylene-4-substituted urazole herbicides | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1981-02-10 | — | — | US | disclosed |
| US-4162315-A | 1,2-(TETRAMETHYLENE)-4-(3,5-DICHLOROPHENYL)URAZOLES | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1979-07-24 | — | — | US | disclosed |
| US-4049820-A | Substituted urazole and thiourazole compounds as agricultural fungicidal agents | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) | 1977-09-20 | — | — | US | disclosed |