Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 6/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10985718 | 0.84 | TSHR (0.40) | SMN1; SMN2LMNAPOLBALDH1A1ATM | |
| SCHEMBL2911507 | 0.79 | MMP3 (0.40) | SMN1; SMN2LMNAPOLBALDH1A1ATM | |
| SCHEMBL112600 | 0.78 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNAPOLBALDH1A1ATM | |
| SCHEMBL10992964 | 0.77 | ALDH1A1 (0.40) | SMN1; SMN2LMNAPOLBALDH1A1ATM | |
| Hydrochloric Acid SCHEMBL10956630 | 0.77 | MMP3 (0.39) | SMN1; SMN2POLBALDH1A1ATMHPGD | |
| SCHEMBL18760256 | 0.76 | POLB (0.63) | SMN1; SMN2LMNAPOLBALDH1A1ATM | |
| SCHEMBL17017 | 0.76 | POLB (0.63) | SMN1; SMN2LMNAPOLBALDH1A1ATM | |
| SCHEMBL5820669 | 0.76 | POLB (0.63) | SMN1; SMN2LMNAPOLBALDH1A1ATM | |
| SCHEMBL4082478 | 0.75 | POLB (0.61) | SMN1; SMN2LMNAPOLBALDH1A1ATM | |
| Hydrochloric Acid SCHEMBL1111003 | 0.75 | POLB (0.61) | SMN1; SMN2LMNAPOLBALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2873665-A1 | Antiviral compounds | Gilead Pharmasset LLC (US) | 2015-05-20 | — | — | EP | disclosed |
| EP-2857394-A1 | Antiviral compounds | Gilead Pharmasset LLC (US) | 2015-04-08 | — | — | EP | disclosed |