Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11368635 | 0.98 | MMP3 (0.42) | MMP3CA2CHKAHPGDCHRNB2 | |
| SCHEMBL10992964 | 0.81 | ALDH1A1 (0.40) | MMP3CA2CHKATSHRKMT2A | |
| SCHEMBL1654758 | 0.79 | HPGD (0.44) | MMP3CA2CHKAHPGDKMT2A | |
| SCHEMBL2911507 | 0.78 | MMP3 (0.40) | MMP3TSHRKMT2AMEN1GAA | |
| SCHEMBL11375222 | 0.77 | MMP3 (0.36) | MMP3CA2CHKA | |
| SCHEMBL4923319 | 0.77 | HPGD (0.41) | MMP3HPGDKMT2AMEN1USP2 | |
| Hydrochloric Acid SCHEMBL10956630 | 0.77 | MMP3 (0.39) | MMP3HPGDTSHRKMT2AMEN1 | |
| SCHEMBL2505898 | 0.77 | MMP3 (0.41) | MMP3CA2CHKAALDH1A1TDP1 | |
| SCHEMBL3466500 | 0.76 | CA2 (0.43) | MMP3CA2CHKAHPGDGAA | |
| SCHEMBL1919225 | 0.76 | CA2 (0.43) | MMP3CA2CHKAHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111386279-A | Glycyrrhetinic acid derivatives for treating hyperkalemia | 阿德利克斯股份有限公司 | 2020-07-07 | — | — | CN | disclosed |