Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PEPD | P12955 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | YARS1 | P54577 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10993260 | 0.87 | PEPD (0.38) | PEPDFOLH1NAALAD2LMNAANPEP | |
| SCHEMBL10972167 | 0.87 | PEPD (0.42) | PEPDFOLH1NAALAD2LMNAANPEP | |
| SCHEMBL10966248 | 0.84 | ALDH1A1 (0.44) | LMNAALDH1A1GAACA2PRSS1 | |
| SCHEMBL7472114 | 0.77 | PRSS1 (0.38) | FOLH1ESR1ESR2TSHRPRSS1 | |
| SCHEMBL10972171 | 0.72 | PEPD (0.45) | PEPDFOLH1NAALAD2LMNAKMT2A | |
| SCHEMBL1286910 | 0.72 | ESR1 (0.46) | LMNATDP1ALDH1A1HIF1ATAAR1 | |
| SCHEMBL11215857 | 0.71 | F10 (0.40) | NAALAD2LMNAKMT2AALDH1A1PRSS1 | |
| SCHEMBL10966252 | 0.70 | TACR3 (0.49) | LMNAALDH1A1GAACA2CYP3A4 | |
| SCHEMBL10332569 | 0.70 | LMNA (0.50) | LMNAALDH1A1GAACA2SRC | |
| SCHEMBL28160803 | 0.70 | CA1 (0.50) | NAALAD2LMNAALDH1A1GAACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4407815-A | AMINO ACID DERIVATIVE ANTIBIOTICS | BEECHAM GROUP LIMITED (GB) | 1983-10-04 | — | — | US | claimed |
| US-4517124-A | REACTION OF A MERCAPTAN TO FORM ANTIVIOTIC | BEECHAM GROUP LIMITED (GB) | 1985-05-14 | — | — | US | disclosed |
| EP-0034443-B1 | BETA-LACTAM ANTIBACTERIAL COMPOUNDS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1984-09-26 | — | — | EP | disclosed |
| US-4463010-A | 1-Aza-[3.2.0]-bicycloheptane-2-carboxylic acid, ester or salt thereof | BEECHAM GROUP P.L.C. (GB) | 1984-07-31 | — | — | US | disclosed |
| EP-0084730-A1 | Esters of penicillin derivatives with beta-lactamase inhibitors, their preparation and their use | BEECHAM GROUP PLC (GB) | 1983-08-03 | — | — | EP | disclosed |
| US-4387051-A | β-Lactam antibiotics, their preparation and their use in pharmaceutical compositions | BEECHAM GROUP LIMITED (GB) | 1983-06-07 | — | — | US | disclosed |