Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 3/20 | 0.38 |
| ▸ | TMPRSS15 | P98073 | 3/20 | 0.38 |
| ▸ | TACR3 | P29371 | 2/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15962588 | 0.84 | CTSS (0.49) | MIFLY96ESR1ESR2ADRB2 | |
| SCHEMBL8601269 | 0.80 | MIF (0.36) | TACR3MIFLY96ESR1ESR2 | |
| SCHEMBL10993260 | 0.78 | PEPD (0.38) | TACR3ESR1ESR2TSHRFOLH1 | |
| SCHEMBL7467548 | 0.77 | LY96 (0.53) | LY96ESR1ESR2CTSSCTSK | |
| SCHEMBL7469618 | 0.77 | ESR1 (0.43) | MIFLY96ESR1ESR2ADRB2 | |
| SCHEMBL10993256 | 0.77 | PEPD (0.37) | PRSS1TMPRSS15ESR1ESR2TSHR | |
| SCHEMBL2582580 | 0.77 | CTSS (0.48) | TACR3MIFESR1ESR2CTSS | |
| SCHEMBL1554126 | 0.77 | CTSS (0.48) | TACR3MIFESR1ESR2CTSS | |
| SCHEMBL1554122 | 0.77 | CTSS (0.48) | TACR3MIFESR1ESR2CTSS | |
| SCHEMBL11519796 | 0.77 | CTSS (0.48) | MIFCTSSCTSKFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-B1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO MCNEIL PHARM INC (US) | 2002-12-18 | — | — | EP | disclosed |