SCHEMBL10993290

SCHEMBL10993290

Cc1ccnc(C)c1C.O=Cc1ccc(C=O)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.46
ALDH1A1 P00352 7/20 0.43
NOS3 P29474 1/20 0.42
NOS2 P35228 1/20 0.42
BRD4 O60885 1/20 0.40
KDM4E B2RXH2 4/20 0.39
LMNA P02545 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TYR P14679 1/20 0.38
CYP2A13 Q16696 1/20 0.38
HSD17B10 Q99714 1/20 0.37
ALDH5A1 P51649 1/20 0.37
ABAT P80404 1/20 0.37
ALDH1A3 P47895 2/20 0.35
ALDH3A1 P30838 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
CCR1 P32246 1/20 0.34
CCR5 P51681 1/20 0.34
CCR8 P51685 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formamide SCHEMBL4091594 0.83 NOS2 (0.50) CYP2A6ALDH1A1NOS3NOS2KDM4E
SCHEMBL7488 0.82
Hydrochloric Acid SCHEMBL27389327 0.80 NOS2 (0.54) CYP2A6ALDH1A1NOS3NOS2KDM4E
Ammonia Solution, Strong SCHEMBL22612697 0.80 NOS2 (0.54) CYP2A6ALDH1A1NOS3NOS2KDM4E
Iodide SCHEMBL27713885 0.80 NOS2 (0.54) CYP2A6ALDH1A1NOS3NOS2KDM4E
Iodide SCHEMBL11070568 0.80 NOS2 (0.54) CYP2A6ALDH1A1NOS3NOS2KDM4E
Bromide SCHEMBL10623434 0.80 NOS2 (0.54) CYP2A6ALDH1A1NOS3NOS2KDM4E
Fluoride SCHEMBL2020932 0.80 NOS2 (0.54) CYP2A6ALDH1A1NOS3NOS2KDM4E
SCHEMBL29125217 0.80
Hydrochloric Acid SCHEMBL1936574 0.80 NOS2 (0.54) CYP2A6ALDH1A1NOS3NOS2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4540770-A Polystyrylpyridine resins having an increased toughness, and composite materials comprising these resins SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) 1985-09-10 US disclosed