SCHEMBL109933

SCHEMBL109933

Nc1ccc(N(CCO)CC(O)CN(CCO)c2ccc(N)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.44
TDP1 Q9NUW8 4/20 0.44
L3MBTL1 Q9Y468 3/20 0.44
CYP3A4 P08684 3/20 0.44
TSHR P16473 3/20 0.44
MAPK1 P28482 2/20 0.44
PSMD14 O00487 1/20 0.44
RECQL P46063 1/20 0.44
GFER P55789 1/20 0.44
KDM4E B2RXH2 4/20 0.40
TP53 P04637 2/20 0.34
ALOX15 P16050 1/20 0.34
MAPT P10636 3/20 0.33
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
ATM Q13315 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5582429 0.98 KDM4E (0.42) ALDH1A1TDP1L3MBTL1CYP3A4TSHR
Hydrochloric Acid SCHEMBL9725229 0.96 KDM4E (0.41) ALDH1A1TDP1L3MBTL1CYP3A4TSHR
SCHEMBL2032769 0.86 ALDH1A1 (0.41) ALDH1A1TDP1L3MBTL1CYP3A4TSHR
SCHEMBL1293392 0.86 TDP1 (0.46) ALDH1A1TDP1L3MBTL1CYP3A4TSHR
SCHEMBL33874 0.84 ALDH1A1 (0.54) ALDH1A1TDP1L3MBTL1CYP3A4TSHR
SCHEMBL8521178 0.84 ALDH1A1 (0.54) ALDH1A1TDP1L3MBTL1CYP3A4TSHR
SCHEMBL28087334 0.84 ALDH1A1 (0.54) ALDH1A1TDP1L3MBTL1CYP3A4TSHR
SCHEMBL33796 0.82 ALDH1A1 (0.52) ALDH1A1TDP1L3MBTL1CYP3A4TSHR
Water SCHEMBL3359653 0.82 ALDH1A1 (0.52) ALDH1A1TDP1L3MBTL1CYP3A4TSHR
Hydrochloric Acid SCHEMBL8756114 0.82 ALDH1A1 (0.52) ALDH1A1TDP1L3MBTL1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2507 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12178897-B2 Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations HENKEL AG & CO. KGAA (DE) 2024-12-31 US claimed
US-12109291-B2 Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations HENKEL AG & CO. KGAA (DE) 2024-10-08 US claimed
US-12102704-B2 Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations HENKEL AG & CO. KGAA (DE) 2024-10-01 US claimed
US-12097274-B2 Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations HENKEL AG & CO. KGAA (DE) 2024-09-24 US claimed
US-12070517-B2 Thickened alkalyzation component for oxidative hair dyeing product HENKEL AG & CO. KGAA (DE) 2024-08-27 US claimed
US-11918671-B2 Multi-tone hair dyeing method in three steps HENKEL AG & CO. KGAA (DE) 2024-03-05 US claimed
US-20230338267-A1 THICKENED ALKALYZATION COMPONENT FOR OXIDATIVE HAIR DYEING PRODUCT HENKEL AG & CO. KGAA (DE) 2023-10-26 US claimed
US-20230310296-A1 Oxidative Dyeing Agent For Keratin Fibers Comprising Novel Dye Precursor Combinations HENKEL AG & CO. KGAA (DE) 2023-10-05 US claimed
WO-2023163907-A1 OXIDATIVE DYEING AGENT FOR KERATIN FIBERS COMPRISING NOVEL DYE PRECURSOR COMBINATIONS HENKEL AG & CO. KGAA (DE) 2023-08-31 WO claimed
US-20230270647-A1 Oxidative Dyeing Agent For Keratin Fibers Comprising Novel Dye Precursor Combinations HENKEL AG & CO. KGAA (DE) 2023-08-31 US claimed
EP-0360644-B1 OXIDATION DYEING COMPOSITION CONTAINING AT LEAST ONE DOUBLE AND AT LEAST ONE SINGLE DYEING BASE, AND DYEING PROCESS MAKING USE OF SUCH A COMPOSITION L'OREAL (FR) 1993-02-17 EP claimed
WO-1992018093-A1 METHOD FOR DYEING KERATIN FIBRES WITH AMINOINDOLES HAVING ALKALINE pH, AND COMPOSITIONS THEREFOR L'OREAL (FR) 1992-10-29 WO claimed
WO-1992017157-A1 NOVEL KERATIN FIBRE DYEING METHOD USING AMINOINDOLES, WITH ACID pH, COMPOSITIONS THEREFOR AND NOVEL AMINOINDOLE COMPOUNDS L'OREAL (FR) 1992-10-15 WO claimed
EP-0506549-A1 Dyeing composition for keratinous fibers containing oxidation dye precursors and hydroxybenzofurans as couplers and dyeing process making use of such a composition L'OREAL (FR) 1992-09-30 EP claimed
EP-0502784-A1 Keratinous fibres dyeing process with isatin or derivatives thereof associated with a tri-, tetra- or pentasubstituted aniline or a bisphenylalkylenediamine and dyeing agents L'OREAL (FR) 1992-09-09 EP claimed
US-5137538-A P-Phenylenediamine and N,N'-diphenylalkylenediamines; uniform color on bleached or permed hair L'OREAL (FR) 1992-08-11 US claimed
US-5114429-A ALIPHATIC ALPHA, OMEGA-DIAMINE COMPOUNDS AND THEIR USE IN HAIR DYEING L'OREAL (FR) 1992-05-19 US claimed
EP-0428441-A2 Keratinic fibre dyeing compostions containing oxydation dye precursors and derivatives of 4-hydroxyindole as couplers, and dyeing process using same L'OREAL (FR) 1991-05-22 EP claimed
EP-0428442-A1 Composition comprising derivatives of 6- or 7-hydroxyindole as couplers and dyeing processes using same L'OREAL (FR) 1991-05-22 EP claimed
EP-0358550-A2 Process for the preparation of aliphatic alpha-, omega-diamines, new compounds and their use in hair dying L'OREAL (FR) 1990-03-14 EP claimed