SCHEMBL28087334

SCHEMBL28087334

Nc1ccc(N(CCO)CCO)cc1.Nc1ccc(N)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.54
TDP1 Q9NUW8 8/20 0.54
CYP3A4 P08684 7/20 0.54
MAPK1 P28482 3/20 0.54
L3MBTL1 Q9Y468 3/20 0.54
TSHR P16473 3/20 0.54
GFER P55789 2/20 0.54
PSMD14 O00487 2/20 0.54
RECQL P46063 1/20 0.54
TP53 P04637 3/20 0.42
ALOX15 P16050 3/20 0.42
MAPT P10636 7/20 0.39
KDM4E B2RXH2 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
KMT2A Q03164 5/20 0.39
MEN1 O00255 3/20 0.39
SMN1; SMN2 Q16637 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8521178 1.00 ALDH1A1 (0.54) ALDH1A1TDP1CYP3A4MAPK1L3MBTL1
SCHEMBL33874 1.00 ALDH1A1 (0.54) ALDH1A1TDP1CYP3A4MAPK1L3MBTL1
Hydrochloric Acid SCHEMBL7714474 0.98 ALDH1A1 (0.52) ALDH1A1TDP1CYP3A4MAPK1L3MBTL1
SCHEMBL33796 0.98 ALDH1A1 (0.52) ALDH1A1TDP1CYP3A4MAPK1L3MBTL1
Water SCHEMBL3359653 0.98 ALDH1A1 (0.52) ALDH1A1TDP1CYP3A4MAPK1L3MBTL1
Hydrochloric Acid SCHEMBL8756114 0.98 ALDH1A1 (0.52) ALDH1A1TDP1CYP3A4MAPK1L3MBTL1
Hydrochloric Acid SCHEMBL9637634 0.96 ALDH1A1 (0.50) ALDH1A1TDP1CYP3A4MAPK1L3MBTL1
SCHEMBL14940571 0.94 ALDH1A1 (0.48) ALDH1A1TDP1CYP3A4MAPK1L3MBTL1
SCHEMBL34106 0.94 ALDH1A1 (0.48) ALDH1A1TDP1CYP3A4MAPK1L3MBTL1
SCHEMBL23839781 0.92 ALDH1A1 (0.47) ALDH1A1TDP1CYP3A4MAPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103589530-B Delivery of particles 宝洁公司 2016-08-24 CN disclosed