Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10966952 | 0.94 | KDM4E (0.47) | HTTALDH1A1BLMKMT2AKDM4E | |
| SCHEMBL9835390 | 0.87 | KDM4E (0.54) | HTTALDH1A1BLMKMT2AKDM4E | |
| SCHEMBL10994286 | 0.80 | ALDH1A1 (0.55) | HTTALDH1A1BLMKMT2AL3MBTL1 | |
| SCHEMBL10994902 | 0.79 | ALDH1A1 (0.49) | ALDH1A1KMT2AKDM4EHPGDRAB9A | |
| SCHEMBL17736334 | 0.76 | MCHR1 (0.47) | HTTALDH1A1KMT2AL3MBTL1USP2 | |
| SCHEMBL10966470 | 0.74 | ALDH1A1 (0.52) | HTTALDH1A1BLMKMT2AKDM4E | |
| SCHEMBL25989656 | 0.74 | ALDH1A1 (0.52) | HTTALDH1A1KMT2AL3MBTL1USP2 | |
| SCHEMBL11034497 | 0.72 | TSHR (0.43) | ALDH1A1KMT2AKDM4EUSP2TSHR | |
| SCHEMBL19721600 | 0.72 | MCHR1 (0.51) | HTTALDH1A1BLMKMT2AKDM4E | |
| SCHEMBL13150784 | 0.72 | MEN1 (0.64) | ALDH1A1BLMKMT2AUSP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4523013-A | 4-Acyl-2,6-dioxo-1-phenethyl piperozines | SANOFI, S.A. (FR) | 1985-06-11 | — | — | US | disclosed |