Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10966470 | 0.84 | ALDH1A1 (0.52) | ALDH1A1BLMKDM4EKMT2AKEAP1 | |
| SCHEMBL9835140 | 0.79 | ALDH1A1 (0.57) | ALDH1A1BLMKDM4EKMT2AKEAP1 | |
| SCHEMBL10966952 | 0.79 | KDM4E (0.47) | ALDH1A1BLMKDM4EKMT2AKEAP1 | |
| SCHEMBL10994286 | 0.77 | ALDH1A1 (0.55) | ALDH1A1BLMKMT2AHPGDHTT | |
| SCHEMBL9835390 | 0.74 | KDM4E (0.54) | ALDH1A1BLMKDM4EKMT2AKEAP1 | |
| SCHEMBL13150784 | 0.73 | MEN1 (0.64) | ALDH1A1BLMKMT2ATSHRMEN1 | |
| SCHEMBL8894163 | 0.73 | P2RX3 (0.50) | MCHR1ALDH1A1MAPK1 | |
| SCHEMBL28544382 | 0.73 | HPGD (0.46) | ALDH1A1BLMKDM4EKMT2AHPGD | |
| SCHEMBL10947749 | 0.72 | KMT2A (0.76) | ALDH1A1KDM4EKMT2AHPGDTSHR | |
| SCHEMBL10993438 | 0.72 | HTT (0.45) | ALDH1A1BLMKDM4EKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3257852-A1 | PREPARATION METHOD FOR PRAZIQUANTEL AND INTERMEDIATE COMPOUNDS THEREOF | Zhejiang Hisun Pharmaceutical Co., Ltd. (CN) | 2017-12-20 | — | — | EP | disclosed |