Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10966601 | 0.81 | ALDH1A1 (0.72) | ALDH1A1HPGDKMT2AMEN1KCNH2 | |
| SCHEMBL10993438 | 0.79 | HTT (0.45) | ALDH1A1HPGDKMT2AMEN1NPC1 | |
| SCHEMBL18127026 | 0.74 | ALDH1A1 (0.53) | ALDH1A1HPGDKMT2AMEN1NPC1 | |
| SCHEMBL17736334 | 0.73 | MCHR1 (0.47) | ALDH1A1KMT2AMEN1SIGMAR1MAPT | |
| SCHEMBL10968730 | 0.71 | ALDH1A1 (0.76) | ALDH1A1HPGDKMT2AMEN1KCNH2 | |
| SCHEMBL9835390 | 0.70 | KDM4E (0.54) | ALDH1A1HPGDKMT2AMEN1KDM4E | |
| SCHEMBL11034497 | 0.68 | TSHR (0.43) | ALDH1A1KMT2AMEN1KCNH2SIGMAR1 | |
| SCHEMBL22980550 | 0.68 | PTGER4 (0.44) | ALDH1A1 | |
| SCHEMBL18127029 | 0.68 | DRD2 (0.52) | ALDH1A1HPGDKMT2AMEN1NPC1 | |
| SCHEMBL11026816 | 0.68 | KMT2A (0.46) | ALDH1A1HPGDKMT2AMEN1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4523013-A | 4-Acyl-2,6-dioxo-1-phenethyl piperozines | SANOFI, S.A. (FR) | 1985-06-11 | — | — | US | disclosed |