Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 11/20 | 0.61 |
| ▸ | RAB9A | P51151 | 8/20 | 0.57 |
| ▸ | NPC1 | O15118 | 7/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.57 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10992370 | 0.89 | RAB9A (0.69) | TBK1RAB9ANPC1RXFP1KDM4E | |
| SCHEMBL9208121 | 0.83 | RAB9A (0.81) | TBK1RAB9ANPC1RXFP1IKBKE | |
| SCHEMBL9205610 | 0.82 | RAB9A (0.66) | TBK1RAB9ANPC1RXFP1IKBKE | |
| SCHEMBL9204045 | 0.81 | RAB9A (0.65) | TBK1RAB9ANPC1RXFP1IKBKE | |
| SCHEMBL11110654 | 0.81 | RAB9A (0.61) | TBK1RAB9ANPC1RXFP1IKBKE | |
| SCHEMBL10991723 | 0.78 | RAB9A (0.58) | TBK1RAB9ANPC1RXFP1IKBKE | |
| SCHEMBL10987502 | 0.77 | TBK1 (0.60) | TBK1RAB9ANPC1RXFP1IKBKE | |
| SCHEMBL10993477 | 0.77 | RAB9A (0.56) | TBK1RAB9ANPC1RXFP1IKBKE | |
| SCHEMBL19182248 | 0.76 | TBK1 (1.00) | TBK1RAB9ANPC1RXFP1IKBKE | |
| SCHEMBL19196856 | 0.75 | TBK1 (0.82) | TBK1RAB9ANPC1RXFP1IKBKE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4539326-A | REACTION OF KETOBENZOPYRAN CARBONITRILE AND KETODICARBOXYLIC ESTER | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-09-03 | — | — | US | disclosed |