Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.81 |
| ▸ | NPC1 | O15118 | 8/20 | 0.81 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.81 |
| ▸ | TBK1 | Q9UHD2 | 6/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9205610 | 0.90 | RAB9A (0.66) | RAB9ANPC1RXFP1TBK1KDM4E | |
| SCHEMBL9204045 | 0.89 | RAB9A (0.65) | RAB9ANPC1RXFP1TBK1KDM4E | |
| SCHEMBL11110654 | 0.86 | RAB9A (0.61) | RAB9ANPC1RXFP1TBK1KDM4E | |
| SCHEMBL9214814 | 0.86 | RAB9A (1.00) | RAB9ANPC1RXFP1TBK1KDM4E | |
| SCHEMBL10987502 | 0.84 | TBK1 (0.60) | RAB9ANPC1RXFP1TBK1KDM4E | |
| SCHEMBL10823671 | 0.84 | RAB9A (0.58) | RAB9ANPC1RXFP1TBK1KDM4E | |
| SCHEMBL10991723 | 0.84 | RAB9A (0.58) | RAB9ANPC1RXFP1TBK1KDM4E | |
| SCHEMBL10993475 | 0.83 | TBK1 (0.61) | RAB9ANPC1RXFP1TBK1KDM4E | |
| SCHEMBL10993477 | 0.82 | RAB9A (0.56) | RAB9ANPC1RXFP1TBK1KDM4E | |
| SCHEMBL19196856 | 0.82 | TBK1 (0.82) | RAB9ANPC1RXFP1TBK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0561845-B1 | PYRIDO-ANELLATED 4-OXO-4H-BENZOPYRANS, A METHOD OF PREPARING THEM, AND THEIR USE AS ANTIDOTES | BASF AG (DE) | 1995-03-08 | — | — | EP | claimed |
| EP-0561845-A1 | PYRIDO-ANELLATED 4-OXO-4H-BENZOPYRANS, A METHOD OF PREPARING THEM, AND THEIR USE AS ANTIDOTES. | BASF AG (DE) | 1993-09-29 | — | — | EP | claimed |
| WO-1992010500-A1 | PYRIDO-ANELLATED 4-OXO-4H-BENZOPYRANS, A METHOD OF PREPARING THEM, AND THEIR USE AS ANTIDOTES | BASF AKTIENGESELLSCHAFT (DE) | 1992-06-25 | — | — | WO | claimed |
| EP-0561845-B1 | PYRIDO-ANELLATED 4-OXO-4H-BENZOPYRANS, A METHOD OF PREPARING THEM, AND THEIR USE AS ANTIDOTES | BASF AG (DE) | 1995-03-08 | — | — | EP | disclosed |