Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10986888 | 0.89 | POLB (0.55) | POLBRAB9AAIMP2LMNAALDH1A1 | |
| SCHEMBL10991908 | 0.89 | RAB9A (0.56) | POLBRAB9AAIMP2LMNAALDH1A1 | |
| SCHEMBL10986641 | 0.88 | POLB (0.54) | POLBRAB9AAIMP2LMNAALDH1A1 | |
| SCHEMBL10991244 | 0.88 | POLB (0.54) | POLBRAB9AAIMP2LMNAALDH1A1 | |
| SCHEMBL10996168 | 0.85 | POLB (0.54) | POLBRAB9AAIMP2LMNAALDH1A1 | |
| SCHEMBL10989692 | 0.85 | ALDH1A1 (0.56) | POLBRAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11000010 | 0.85 | POLB (0.52) | POLBRAB9AAIMP2LMNAALDH1A1 | |
| SCHEMBL10996385 | 0.84 | POLB (0.51) | POLBRAB9AAIMP2LMNAALDH1A1 | |
| SCHEMBL10994397 | 0.84 | ALDH1A1 (0.58) | POLBRAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL10994793 | 0.84 | POLB (0.50) | POLBRAB9AAIMP2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4558129-A | Benzodioxanyl-hydroxyethylene-piperazinyl acetanilides which effect calcium entry and β-blockade | SYNTEX (U.S.A.) INC. (US) | 1985-12-10 | — | — | US | disclosed |