Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10994318 | 0.91 | GRM5 (0.42) | LMNAALDH1A1GRM5POLBKDM4E | |
| SCHEMBL10994147 | 0.90 | ALDH1A1 (0.43) | LMNAMAPK1ALDH1A1GFERGRM5 | |
| SCHEMBL11000472 | 0.87 | GRM5 (0.39) | ATMLMNAALDH1A1GRM5POLB | |
| SCHEMBL10998992 | 0.87 | GRM5 (0.51) | ATMLMNAMAPK1ALDH1A1GRM5 | |
| SCHEMBL10992667 | 0.87 | GRM5 (0.43) | GRM5POLBTP53P2RX7L3MBTL1 | |
| SCHEMBL10992675 | 0.86 | DRD4 (0.41) | ATMLMNAMAPK1ALDH1A1GFER | |
| SCHEMBL11148636 | 0.82 | CYP1A2 (0.40) | ATMLMNAALDH1A1HTTMEN1 | |
| SCHEMBL10998809 | 0.78 | GRM5 (0.45) | ATMLMNAMAPK1ALDH1A1GRM5 | |
| SCHEMBL10994616 | 0.77 | GRM5 (0.49) | LMNAMAPK1ALDH1A1GRM5POLB | |
| SCHEMBL10993280 | 0.77 | GRM5 (0.44) | LMNAMAPK1ALDH1A1GRM5POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4542144-A | EPILEPSY | MCNEILAB INC. (US) | 1985-09-17 | — | — | US | disclosed |