Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10994318 | 0.94 | GRM5 (0.42) | GRM5L3MBTL1P2RX7TP53POLB | |
| SCHEMBL10994616 | 0.90 | GRM5 (0.49) | GRM5L3MBTL1P2RX7PDK1PDK2 | |
| SCHEMBL11000472 | 0.90 | GRM5 (0.39) | GRM5HPGDP2RX7TP53POLB | |
| SCHEMBL10993445 | 0.87 | GRM5 (0.45) | GRM5POLBTDP1 | |
| SCHEMBL10994676 | 0.87 | ATM (0.38) | GRM5L3MBTL1HPGDP2RX7TP53 | |
| SCHEMBL10998692 | 0.86 | GRM5 (0.59) | GRM5L3MBTL1HPGDP2RX7PTGS2 | |
| SCHEMBL10994165 | 0.86 | GRM5 (0.46) | GRM5PDK1PDK2PDK3PDK4 | |
| SCHEMBL11148675 | 0.80 | L3MBTL1 (0.52) | L3MBTL1HPGDP2RX7PTGS2GBA1 | |
| SCHEMBL10998809 | 0.80 | GRM5 (0.45) | GRM5L3MBTL1POLBTDP1 | |
| SCHEMBL10993528 | 0.79 | GRM5 (0.58) | GRM5L3MBTL1P2RX7TP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4542144-A | EPILEPSY | MCNEILAB INC. (US) | 1985-09-17 | — | — | US | disclosed |