Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 10/20 | 0.41 |
| ▸ | NPC1 | O15118 | 8/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10991118 | 0.79 | MAPT (0.33) | MAPTHSD17B10RAB9ANPC1FDPS | |
| SCHEMBL10996793 | 0.79 | MAPT (0.33) | MAPTHSD17B10RAB9ANPC1FDPS | |
| SCHEMBL10985936 | 0.73 | MAPT (0.53) | MAPTHSD17B10RAB9ANPC1GAA | |
| SCHEMBL21354116 | 0.70 | RAB9A (0.44) | MAPTHSD17B10RAB9ANPC1FDPS | |
| SCHEMBL10531759 | 0.69 | — | — | |
| SCHEMBL10994240 | 0.68 | MAPT (0.45) | MAPTHSD17B10RAB9ANPC1FDPS | |
| SCHEMBL6374526 | 0.68 | MAPT (0.53) | MAPTHSD17B10RAB9ANPC1GAA | |
| SCHEMBL20187610 | 0.67 | MAPT (0.41) | MAPTRAB9ANPC1FDPSGAA | |
| SCHEMBL20187609 | 0.67 | MAPT (0.41) | MAPTRAB9ANPC1FDPSGAA | |
| SCHEMBL10992289 | 0.67 | GAA (0.45) | MAPTRAB9ANPC1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4491587-A | ANTIALLERGENS, ANTIHISTAMINES, MUSCLE RELAXANTS/ INSULATING POWDER BLANKET ABOVD THE MELT WITH HEAT GENERATED IN THE MELT BY ELECTRIC CURRENT; LOWER TEMPERATURE | MEAD JOHNSON & COMPANY (US) | 1985-01-01 | — | — | US | disclosed |
| US-4223031-A | ANTIALLERGENS, ANTIHISTAMINES, BRONCHODILATOR AGENTS, HYPERSENSITIVITY | MEAD JOHNSON & COMPANY (US) | 1980-09-16 | — | — | US | disclosed |