Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7430532 | 0.89 | KMT2A (0.39) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10997102 | 0.88 | MEN1 (0.52) | KMT2AMEN1ALDH1A1MAPTCA1 | |
| SCHEMBL11000010 | 0.83 | POLB (0.52) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10989717 | 0.83 | ALDH1A1 (0.49) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10995435 | 0.82 | UGCG (0.32) | — | |
| SCHEMBL10994841 | 0.81 | ALDH1A1 (0.43) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10995111 | 0.81 | LMNA (0.50) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10994260 | 0.79 | POLB (0.50) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10993684 | 0.78 | ALDH1A1 (0.48) | KMT2AMEN1ALDH1A1MAPTCA1 | |
| SCHEMBL10991656 | 0.78 | ALDH1A1 (0.61) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4558129-A | Benzodioxanyl-hydroxyethylene-piperazinyl acetanilides which effect calcium entry and β-blockade | SYNTEX (U.S.A.) INC. (US) | 1985-12-10 | — | — | US | disclosed |