Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10995442 | 0.89 | KMT2A (0.44) | KMT2AMEN1SMN1; SMN2LMNAGAA | |
| SCHEMBL7440389 | 0.89 | MEN1 (0.47) | KMT2AMEN1SMN1; SMN2LMNAPOLB | |
| SCHEMBL7434317 | 0.85 | POLB (0.46) | KMT2AMEN1SMN1; SMN2LMNAGAA | |
| SCHEMBL7437133 | 0.84 | ALDH1A1 (0.44) | KMT2AMEN1SMN1; SMN2LMNAGAA | |
| SCHEMBL7430526 | 0.83 | SPHK1 (0.30) | — | |
| SCHEMBL7446165 | 0.83 | TSHR (0.43) | KMT2AMEN1SMN1; SMN2LMNAGAA | |
| SCHEMBL7445143 | 0.82 | POLB (0.42) | KMT2AMEN1SMN1; SMN2LMNAGAA | |
| SCHEMBL7440717 | 0.80 | POLB (0.45) | KMT2AMEN1SMN1; SMN2LMNAGAA | |
| SCHEMBL7495736 | 0.80 | TSHR (0.49) | KMT2AMEN1LMNAGAAHTT | |
| SCHEMBL7437024 | 0.79 | LMNA (0.45) | KMT2AMEN1SMN1; SMN2LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |