Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | GFER | P55789 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.48 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13797740 | 0.89 | MAPT (0.50) | ALDH1A1L3MBTL1TSHRGFERMAPK1 | |
| SCHEMBL23822860 | 0.89 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1TSHRGFERMAPK1 | |
| SCHEMBL8028832 | 0.85 | KMT2A (0.42) | ALDH1A1L3MBTL1TSHRGFERMAPK1 | |
| SCHEMBL5136014 | 0.82 | CNR2 (0.43) | TDP1KDM4ECNR2 | |
| SCHEMBL1735497 | 0.80 | ALDH1A1 (0.74) | ALDH1A1L3MBTL1TSHRGFERMAPK1 | |
| SCHEMBL560649 | 0.79 | EGFR (0.41) | ALDH1A1KDM4EGAACNR2MAPT | |
| SCHEMBL1478591 | 0.78 | HDAC8 (0.43) | ALDH1A1L3MBTL1CYP3A4TDP1KDM4E | |
| SCHEMBL2902079 | 0.77 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1TSHRGFERMAPK1 | |
| SCHEMBL24023771 | 0.77 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1TSHRGFERMAPK1 | |
| SCHEMBL195134 | 0.77 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1TSHRGFERMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970696-B | Coumarin oxime ester photoinitiator | 江南大学 | 2022-12-23 | — | — | CN | claimed |
| CN-114249696-B | Luminol compound, preparation method and application thereof, and pharmaceutical composition | 四川大学 | 2023-05-12 | — | — | CN | disclosed |
| CN-109970696-B | Coumarin oxime ester photoinitiator | 江南大学 | 2022-12-23 | — | — | CN | disclosed |
| CN-114249696-A | Luminol compound, preparation method and application thereof, and pharmaceutical composition | 四川大学 | 2022-03-29 | — | — | CN | disclosed |
| EP-2683714-B1 | II (PI)-CONJUGATED FLUOROIONOPHORES AND METHOD FOR DETERMINING AN ALKALI ION | UNIV POTSDAM (DE) | 2019-01-09 | — | — | EP | disclosed |
| EP-2683714-B1 | II (PI)-CONJUGATED FLUOROIONOPHORES AND METHOD FOR DETERMINING AN ALKALI ION | UNIV POTSDAM (DE) | 2019-01-09 | — | — | EP | disclosed |
| EP-1763509-B1 | ALPHA-HELICAL MIMETICS | WALTER & ELIZA HALL INST MEDICAL RES (AU) | 2018-02-21 | — | — | EP | disclosed |
| US-9493478-B2 | Fused ring compound containing furan or salt thereof and pharmaceutical composition comprising same | YUHAN CORPORATION (KR) | 2016-11-15 | — | — | US | disclosed |
| WO-2016087596-A1 | SECURININE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER | PIERRE FABRE MEDICAMENT (FR) | 2016-06-09 | — | — | WO | disclosed |
| US-20150191478-A1 | FUSED RING COMPOUND CONTAINING FURAN OR SALT THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | YUHAN CORPORATION (KR) | 2015-07-09 | — | — | US | disclosed |
| US-8153446-B2 | Fluorogenic compounds converted to fluorophores by photochemical or chemical means and their use in biological systems | KENT STATE UNIVERSITY (US) | 2012-04-10 | — | — | US | disclosed |
| US-7956216-B2 | Benzoyl urea derivatives mimicing BH3-only proteins, able to interact with a Bcl-2 protein | THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) | 2011-06-07 | — | — | US | disclosed |
| US-7956216-B2 | Benzoyl urea derivatives mimicing BH3-only proteins, able to interact with a Bcl-2 protein | THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) | 2011-06-07 | — | — | US | disclosed |
| US-20100029952-A1 | Fluorogenic compounds converted to fluorophores by photochemical or chemical means and their use in biological systems | KENT STATE UNIVERSITY (US) | 2010-02-04 | — | — | US | disclosed |
| US-20100029952-A1 | Fluorogenic compounds converted to fluorophores by photochemical or chemical means and their use in biological systems | KENT STATE UNIVERSITY (US) | 2010-02-04 | — | — | US | disclosed |
| US-20100029952-A1 | Fluorogenic compounds converted to fluorophores by photochemical or chemical means and their use in biological systems | KENT STATE UNIVERSITY (US) | 2010-02-04 | — | — | US | disclosed |
| US-20090299049-A1 | Bicyclic Compounds and Their Use | REPLIZYME LIMITED (GB) | 2009-12-03 | — | — | US | disclosed |
| US-20080153802-A1 | Alpha-helical mimetics | THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) | 2008-06-26 | — | — | US | disclosed |
| US-20080153802-A1 | Alpha-helical mimetics | THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) | 2008-06-26 | — | — | US | disclosed |
| WO-2007091056-A2 | BICYCLIC COMPOUNDS AND THEIR USE | THE UNIVERSITY OF YORK (GB) | 2007-08-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150191478-A1 | FUSED RING COMPOUND CONTAINING FURAN OR SALT THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | PIK3CD, PIK3CA, MTOR | ALDH1A1 3470/4885L3MBTL1 4873/4885TSHR 4514/4885 |
| US-20080153802-A1 | Alpha-helical mimetics | BID, BAX, BAD | ALDH1A1 4208/4885L3MBTL1 85/4885TSHR 4259/4885 |
| US-20100029952-A1 | Fluorogenic compounds converted to fluorophores by photochemical or chemical means and their use in biological systems | MPI, ACR, PFAS | ALDH1A1 1056/4885L3MBTL1 1877/4885TSHR 2426/4885 |
| US-20090299049-A1 | Bicyclic Compounds and Their Use | ERCC4, PARP1, ERCC5 | ALDH1A1 1108/4885L3MBTL1 838/4885TSHR 4050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.