SCHEMBL10996089

SCHEMBL10996089

O=C(O)Nc1ccc(O)c(Cc2ccccc2)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.54
CYP3A4 P08684 1/20 0.54
HPGD P15428 1/20 0.54
ALOX15 P16050 1/20 0.54
KMT2A Q03164 1/20 0.54
HIF1A Q16665 1/20 0.54
HSD17B10 Q99714 1/20 0.54
SLC7A5 Q01650 1/20 0.51
BCL2 P10415 3/20 0.50
BCL2L1 Q07817 1/20 0.50
HNF4A P41235 1/20 0.45
ALOX5 P09917 1/20 0.45
ERCC1 P07992 1/20 0.44
ERCC4 Q92889 1/20 0.44
IDH1 O75874 1/20 0.43
PTPN1 P18031 2/20 0.43
PTPN2 P17706 1/20 0.43
PTPN6 P29350 1/20 0.43
LDHA P00338 1/20 0.43
LDHB P07195 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8416762 0.85 GAA (0.53) MEN1CYP3A4HPGDALOX15KMT2A
SCHEMBL4689214 0.81 ALDH1A1 (0.47) MEN1CYP3A4KMT2AERCC1ERCC4
SCHEMBL30097168 0.80 XDH (0.54) MEN1CYP3A4ALOX15KMT2AHIF1A
SCHEMBL23705278 0.80 XDH (0.54) MEN1CYP3A4ALOX15KMT2AHIF1A
SCHEMBL3773254 0.77 SLC1A3 (0.58) MEN1HPGDKMT2APTPN1
SCHEMBL9651071 0.75 MEN1 (0.59) MEN1CYP3A4HPGDALOX15KMT2A
SCHEMBL4689124 0.74 KDM4C (0.49) MEN1CYP3A4HPGDKMT2AEGFR
SCHEMBL2251164 0.74 CYP3A4 (0.62) MEN1CYP3A4HPGDALOX15KMT2A
SCHEMBL10886054 0.73 IDH1 (0.70) MEN1CYP3A4HPGDALOX15KMT2A
SCHEMBL390179 0.73 ALOX5 (0.71) MEN1CYP3A4HPGDALOX15KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4557618-A PHENOLIC DEVELOPER AND ELECTRON DONATING COLORLESS DYE; DESENSITIZING COMPOUND PENTEL KABUSHIKI KAISHA (JP) 1985-12-10 US disclosed